What is Meropenem Avibactam Injection?

Meropenem Avibactam Injection is a combination antibiotic useful in treating complicated urinary tract infections (UTIs) which include pyelonephritis and other infections caused due to susceptible gram-negative bacteria. It is completely safe to buy from www.saturnformulations.in at the most affordable price in India.

Uses of Meropenem Avibactam Injection

The combination of Meropenem Avibactam Injection is a combination antibiotic useful in treating severe bacterial infections especially those caused by drug-resistant bacteria. This includes meropenem, a carbapenem antibiotic which inhibits bacterial cell wall formation. Along with this avibactam that is a β-lactamase inhibitor, protects meropenem from degrading enzymes. Hence, this makes the combination effective against resistant bacteria.

Moreover this combination injection is useful in complex urinary tract infections (CUTI) and is helpful in complicated intra-abdominal infections (CIAI). Also hospital-acquired pneumonia (HAP) and ventilator associated pneumonia (VAP) are other multidrug-resistant illnesses. As a result, this shows several health benefits of this combination injection.

• Complicated Intra-abdominal Infections (cIAI) – Used with metronidazole for abdominal infections.
• Complicated Urinary Tract Infections (cUTI) – Including pyelonephritis caused by drug-resistant bacteria.
• Hospital-Acquired & Ventilator-Associated Pneumonia (HAP/VAP) – Effective against multi-drug resistant bacteria.

• Carbapenem-resistant Enterobacteriaceae (CRE) – Used for infections caused by highly resistant bacteria.
• Extended-Spectrum Beta-Lactamase (ESBL) Producing Bacteria – Treats infections resistant to common antibiotics.

Precautions and Side Effects of Avibactam Meropenem Injection

• Allergy Check – Inform your healthcare provider if you are allergic to meropenem, avibactam, or any other beta-lactam antibiotics.
• Kidney Function – Patients with kidney disease may require dosage adjustments.
• Seizure Risk – Use with caution in individuals with a history of seizures or epilepsy.
• Pregnancy & Breastfeeding – Consult a doctor before use during pregnancy or breastfeeding.
• Clostridium difficile Infection – Prolonged use may cause severe diarrhea due to C. difficile infection.
• Liver Function Monitoring – Liver enzyme levels should be monitored in patients with existing liver conditions.
• Drug Interactions – Avoid combining with valproic acid, as it may reduce seizure control.

Side Effects of Meropenem Avibactam Injection

• Nausea
• Vomiting
• Diarrhea
• Headache
• Injection site reactions (pain, swelling, redness)
• Seizures
• Liver dysfunction

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